California
Biotech Insights
February 3, 2026
Recent Funding: TRexBio (SF) Raises Additional $50M to Advance Regulatory T Cell Therapies TRexBio extended its Series B by $50 million, bringing total Series B funding to $134 million, to advance its lead drug TRB-061, now in a Phase 1a/b trial for inflammatory diseases, with an initial focus on atopic dermatitis. The new capital gives […]
January 29, 2026
January 27, 2026
Recent Funding: Mendra (SF) Launches with $82M Series A to Acquire and Commercialize Rare Disease Drugs Mendra raised $82M in a Series A co-led by OrbiMed, 8VC, and 5AM Ventures to identify and acquire underappreciated rare disease medicines that are already post–proof-of-concept or near commercialization. Led by former BioMarin executive Joshua Grass, Mendra plans to […]
January 20, 2026
Recent Funding: Soley Therapeutics (SF) Raises $200M Series C to Advance Stress-Response Drug Platform Soley Therapeutics emerged from stealth with a $200M Series C, bringing total funding to $290M, to advance a drug discovery platform designed to control how cells respond to biological stress – with applications across cancer, obesity, hair loss, and neurodegenerative diseases. […]
January 6, 2026
M&A, Deals, Partnerships: Dynavax Technologies (SF) to Be Acquired by Sanofi for $2.2B Cash Sanofi will buy Dynavax for $2.2 billion in cash ($15.50/share) to add Dynavax’s adult hepatitis B vaccine Heplisav-B (a 2-dose series over 1 month vs. the typical 3 doses over 6 months); Heplisav-B generated $90M in Q3 2025 revenue and Dynavax […]
December 23, 2025
Recent Funding: Aeovian Pharmaceuticals (SF) Raises $55M to Advance Selective mTORC1 Therapy for TSC-Related Epilepsy Aeovian secured $55M to complete a Phase 2 trial of AV078, a brain-penetrant, selective mTORC1 inhibitor designed to reduce seizures in tuberous sclerosis complex (TSC), aiming for improved efficacy and fewer side effects than older drugs like rapamycin and everolimus. […]