Vice President Preclinical Development

Los Angeles

VP Preclinical Development

The company:

Our client is about 150 FTE across two Southern California sites. The culture of the company is fun, fast-paced, and has a clear mission to get therapies into the clinic and to put patients first.  

- Bispecific antibody platform with massive potential

- Strong partnerships

- Great cash position

- Appetite to grow and strong trajectory

- Hunger for innovation and putting things into the clinic

- Science first attitude

- Fun team-oriented environment

- Work with people who are motivated and have a lot of initiative


VP Preclinical Development


- PhD in related discipline

- Strong toxicology and safety background

- Deep regulatory experience

- Taken a lead role in IND and BLA filing

- Independent worker

- Strong manager. A decisive leader, with great soft skills, works well with the team

- If the person comes in with more of a DMPK background, they need to be very senior and have a high level of esteem. Tox background is strongly preferred

- Driven by science and excited about what Xencor is doing

- Some experience in biologics, can't only be a small molecule toxicologist

- Immunology background or exposure is preferred

- Both large pharma and small biotech company experience is preferred

The role:

- Design preclinical safety/ tox strategy and studies

- Design primate studies (about 1-2/ year)

- Oversee all safety studies and overarching safety strategy

- Lead IND enabling efforts (on average 1.5 INDs per year)

- Functional expert within cross-functional teams (clinical, regulatory, quality, etc.)

- Lead the group

- Contribute at the executive level from a strategic, resource, and personnel perspective

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